...

若年女性の冷え症ならびに月経随伴症状への自律神経活

by user

on
Category: Documents
15

views

Report

Comments

Transcript

若年女性の冷え症ならびに月経随伴症状への自律神経活
Kobe University Repository : Kernel
Title
若年女性の冷え症ならびに月経随伴症状への自律神経活
動度の関わり(The modulation of Hiesho and
menstruation related symptoms by autonomic nerve
activity in Japanese young women)
Author(s)
三浦, 史子 / 中井, 佳緒里 / 松尾, 博哉
Citation
神戸大学大学院保健学研究科紀要,28:1-8
Issue date
2012
Resource Type
Departmental Bulletin Paper / 紀要論文
Resource Version
publisher
DOI
URL
http://www.lib.kobe-u.ac.jp/handle_kernel/81004823
Create Date: 2017-03-30
⚄኱㝔ಖ೺⣖せ ➨ ᕳ㸪
৹ා੫଻͈႖̢છ͍̈́ͣͅġ
࠮ࠐଟฺછે͈͒ুၙ૰ࠐ‫ڰ‬൲ഽ͈‫ͤͩ۾‬ġ
୕ᾆ ྐᏊ 1㸪୰஭ె⥴㔛 1㸪ᯇᑿ ༤ဢ 2
せ ᪨
ᮏ◊✲࡛ࡣࠊ෭࠼⑕࡞ࡽࡧ࡟⑓ⓗ᭶⤒㝶క⑕≧࡛࠶ࡿ᭶⤒๓⥭ᙇ⑕㸦PMS㸧ࢆṇ☜࡟ᢕᥱࡋࠊ⮬ᚊ⚄
⤒άືᗘࡀࡇࢀࡽࡢ⑓ែ⏕⌮࡟㛵ࢃࡾࢆ᭷ࡍࡿ࠿࡝࠺࠿ࢆㄪ࡭ࡓࠋᑐ㇟ࡣ⚄ᡞ኱Ꮫ་Ꮫ㒊ಖ೺Ꮫ⛉࡟
ᡤᒓࡍࡿዪᏊᏛ⏕ 50 ྡ࡛࠶ࡿࠋᖺ㱋ࠊయ᱁ࠊ᭶⤒࿘ᮇࠊ෭࠼⑕࡜ PMS ࡢデ᩿ᇶ‽ࠊ⏕ά⩦័࡟㛵ࡍ
ࡿ㉁ၥ⣬ㄪᰝࢆᐇ᪋ࡍࡿ࡜࡜ࡶ࡟ࠊᛶ࿘ᮇࡢ᤼༸๓ᚋ࡛෭Ỉ㈇Ⲵࢸࢫࢺ࡞ࡽࡧ࡟ᚰ㟁ᅗ࿘Ἴᩘゎᯒ࡟
ࡼࡾ⮬ᚊ⚄⤒άືᗘࢆホ౯ࡋࡓࠋ෭Ỉ㈇Ⲵ࡛ࡣࠊ෭࠼⑕⩌ࡣ㠀෭࠼⑕⩌࡟ẚࡋ࡚᤼༸๓ᚋ࡜ࡶ࡟⓶⭵
ᗘࡢᅇ᚟ࡀ᭷ព࡟㐜ᘏࡋࠊ≉࡟ࠊ᤼༸ᚋ࡛㐜ᘏࡢ⛬ᗘࡣ㢧ⴭ࡛࠶ࡗࡓࠋᚰ㟁ᅗ࿘Ἴᩘゎᯒ࡛ࡣࠊPMS
⩌࡟࠾࠸࡚ HF ࡀ᤼༸ᚋ࡛ప್ࢆ♧ࡋࠊ෭࠼⑕ࠊPMS ࡜ࡶ࡟᤼༸ᚋ LF/HF ẚࡀ㧗ࡃ࡞ࡿഴྥࡀほᐹ
ࡉࢀࡓࠋ෭࠼⑕ࠊPMS ࡛ࡣ⮬ᚊ⚄⤒άືㄪ⠇ᶵ⬟ࡢపୗ࠶ࡿ࠸ࡣᨭ㞀ࢆࡁࡓࡋ࡚࠸ࡿࡇ࡜ࠊࡑࡢኻ
ㄪᗘ࡟ࡣᛶ࿘ᮇࡢ᫬ᮇ࡛┦㐪ࡀࡳࡽࢀࡿࡇ࡜ࡀ♧၀ࡉࢀࡓࠋ
⣴ᘬ⏝ㄒ㸸෭࠼⑕ࠊ᭶⤒๓⥭ᙇ⑕ࠊ⮬ᚊ⚄⤒άືᗘࠊ෭Ỉ㈇Ⲵࢸࢫࢺࠊᚰ㟁ᅗ࿘Ἴᩘゎᯒ
Ϩ㸬⥴ゝ
෭࠼⑕ࡸ⑓ⓗ࡞᭶⤒㝶క⑕≧ࡣዪᛶ≉᭷ࡢ᪥ᖖⓗ೺ᗣ㞀ᐖ࡛࠶ࡾࠊࡑࡢ㧗࠸㢖ᗘ࡜࡜ࡶ࡟ዪᛶࡢ
QOL ࢆⴭࡋࡃపୗࡉࡏࡿ 1)ࠋ෭࠼⑕ࡢཎᅉ࡟ࡘ࠸࡚ࡣࠊయ㉁ࡸ㑇ఏⓗせᅉ࡜࡜ࡶ࡟ᛶ࿘ᮇࠊయ᱁ࠊࢲ
࢖࢚ࢵࢺࡸ㣗஦࡞࡝ࡢ⏕ά⩦័ࡸࢫࢺࣞࢫ࡞࡝ࡀ」㞧࡟㛵㐃ࡋ㔜」ࡋ࡚࠸ࡿ࡜᥎ ࡉࢀࡿ 2,3,4)ࠋ୍᪉ࠊ
᭶⤒๓⥭ᙇ⑕㸦௨ୗ PMS㸧ࡸ᭶⤒ᅔ㞴⑕࡜࠸ࡗࡓ᭶⤒㝶క⑕≧ࡣࠊዪᛶ≉᭷ࡢᛶ࿘ᮇ࡟ࡼࡿ࣍ࣝࣔ
ࣥኚື࡟కࡗ࡚ᘬࡁ㉳ࡇࡉࢀࠊయ㉁ࡸ㑇ఏⓗせᅉ࡜࡜ࡶ࡟⏕ά⩦័ࡸࢫࢺࣞࢫ࡞࡝ࡀࡑࡢ⛬ᗘࢆಟ㣭
ࡍࡿࠋᐇ㝿ࠊ୧⪅ࡀేᅾࡋዪᛶࡢ QOL ࢆⴭࡋࡃపୗࡉࡏ࡚࠸ࡿࡇ࡜ࡣᑡ࡞ࡃ࡞࠸ࠋ୧⪅࡟ඹ㏻ࡍࡿ
⑓ែ⏕⌮ࢆ⪃࠼ࡿୖ࡛ࠊࡑࢀࡒࢀከᒱ࡟ࢃࡓࡿཎᅉࡀ᭱⤊ⓗ࡟⮬ᚊ⚄⤒ᶵ⬟࡞ࡽࡧ࡟ࡑࡢᶵ⬟ㄪ⠇ࢆ
௓ࡋ࡚⑕≧Ⓨ⌧࡜ࡑࡢ㔜⑕ᗘࡢᙧᡂ࡟ࡘ࡞ࡀࡗ࡚࠸ࡿࡇ࡜ࡀண ࡉࢀࡿࠋ⮫ᗋⓗ࡟ࠊPMS ࡜᭶⤒ᅔ
㞴⑕ࡢ㔜⑕ᗘ࡟ࡣ┦㛵ࡀ࠶ࡿ࡜࠸࠺ࡇ࡜ࡸ 5)ࠊPMS ࡛ࡣ⮬ᚊ⚄⤒άືᗘࡸ๪஺ឤ⚄⤒άືᗘࡀ᭷ព࡟
ప್ࢆ♧ࡍࡇ࡜ࡀሗ࿌ࡉࢀ࡚࠸ࡿ
6,7)
ࠋࡋ࠿ࡋ࡞ࡀࡽࠊ⑓ⓗ᭶⤒㝶క⑕≧࡞ࡽࡧ࡟෭࠼⑕ࢆ᫂☜࡟デ
᩿ࡋࠊ⮬ᚊ⚄⤒ࡢࡑࢀࡽࡢ⑓ែ⏕⌮࡬ࡢ㛵ࢃࡾࢆᛶ࿘ᮇࡢኚືࡢ୰࡛ホ౯ࡋࡓሗ࿌ࡣࡳࡽࢀ࡞࠸ࠋ
ᮏ◊✲࡛ࡣࠊ෭࠼⑕࡜⑓ⓗ᭶⤒㝶క⑕≧࡛࠶ࡿ PMS ࡜᭶⤒ᅔ㞴⑕ࢆ᫂☜࡟デ᩿ࡍࡿ࡜࡜ࡶ࡟ࠊ⮬
ᚊ⚄⤒άືᗘࢆࠊ෭Ỉ㈇Ⲵࢸࢫࢺ࡜ᚰ㟁ᅗ࿘Ἴᩘゎᯒࢆ⏝࠸࡚ᛶ࿘ᮇࡢ᤼༸๓ᚋ࡛ᢕᥱࡋࠊ⮬ᚊ⚄⤒
ࡢ෭࠼⑕࡞ࡽࡧ࡟⑓ⓗ᭶⤒㝶క⑕≧࡬ࡢ㛵ࢃࡾࢆ᳨ウࡋࡓࠋ
ϩ᪉ἲ
1㸧ᑐ㇟
ᑐ㇟ࡣ⚄ᡞ኱Ꮫ་Ꮫ㒊ಖ೺Ꮫ⛉࡟ᡤᒓࡍࡿዪᏊᏛ⏕ 50 ྡ࡛ࠊෆ⛉ྜే⑕㸦⏥≧⭢⑌ᝈ➼㸧ࡀ࡞ࡃ
⤒ཱྀ㑊ዷ⸆ࢆ౑⏝ࡋ࡚࠸࡞࠸⪅࡜ࡋࡓࠋ㝖እᇶ‽࡟ヱᙜࡍࡿ⪅ࡣࡇࡢ 50 ྡࡢ୰࡟ࡣ࠸࡞࠿ࡗࡓࠋ◊
✲ᮇ㛫ࡣ 2011 ᖺ 9 ᭶~2011 ᖺ 11 ᭶ࠋ⮬ᚊ⚄⤒άືᗘࡢ ᐃࡣ༗ᚋ 12 ᫬ 30 ศࠥ18 ᫬ࡢ㛫࡟ᐇ᪋ࡋࡓࠋ
1
2
⚄ᡞ኱Ꮫ་Ꮫ㒊ಖ೺Ꮫ⛉┳ㆤᏛᑓᨷ
⚄ᡞ኱Ꮫ኱Ꮫ㝔ಖ೺Ꮫ◊✲⛉
㪈
୕ᾆ ᩥᏊ ௚
2㸧᪉ἲ
㸦1㸧㉁ၥ⣬ㄪᰝ
ᖺ㱋ࠊ㌟㛗ࠊయ㔜ࠊᇶ♏⑌ᝈࡢ᭷↓ࠊ᭶⤒࿘ᮇࠊ෭࠼⑕ࡢデ᩿ᇶ‽ࠊPMS ࡢデ᩿ᇶ‽ࠊ෭࠼⑕࡬
ࡢᑐ⟇᪉ἲࠊࢫࢺࣞࢫࠊ㣗஦ࡢᦤࡾ᪉ࠊ╧╀ࠊධᾎࠊࢲ࢖࢚ࢵࢺࠊ㐠ື⩦័࡜࠸ࡗࡓ⏕ά⩦័࡟㛵ࡍ
ࡿ㉁ၥ㡯┠ࢆධࢀࡓ⊂⮬ࡢ⮬グᘧࡢ࢔ࣥࢣ࣮ࢺࢆసᡂࡋࡓࠋ෭࠼࡟ࡣࠕ෭࠼⑕ࠖ
ࠕ෭࠼ᛶࠖ࡜࠸࠺ 2
㏻ࡾࡢ⾲⌧ࡀ࠶ࡾࠊࡇࡢ㐪࠸࡟᫂☜࡞ᐃ⩏ࡣ࡞࠸ࡀࠊᮾὒ་Ꮫ࡟࠾࠸࡚෭࠼ࡣࠕ෭࠼⑕ࠖ࡜ࡋ࡚⑓ែ
ࡢ୍ࡘ࡜ࡋ࡚࡜ࡽ࠼ࡽࢀ࡚࠸ࡿࠋᮏ◊✲࡛ࡣࠕ෭࠼⑕ࠖ࡜グ㍕ࡋࠊデ᩿ᇶ‽ࡣᑎ⃝
1,8)
ࡢ෭࠼⑕ࡢデ
᩿ᇶ‽ࢆ౑⏝ࡋࡓࠋPMS ࡣࠕ᭶⤒㛤ጞ 3㹼10 ᪥๓࠿ࡽጞࡲࡿ㌟యⓗ࣭⢭⚄ⓗ⑕≧࡛᭶⤒㛤ጞ࡜࡜ࡶ
࡟ῶ㏥࡞࠸ࡋᾘኻࡍࡿࡶࡢࠖ࡜᪥ᮏ⏘፬ே⛉Ꮫ఍࡛ᐃ⩏ࡉࢀ࡚࠸ࡿࠋᮏ◊✲࡛ࡣ JF Mortola ࡢデ᩿ᇶ
‽ 9,10)࡟ᚑ࠸ࠊ㌟య⑕≧࣭⢭⚄⑕≧ࢆᣲࡆࠊࡑࢀࡽࡢ⑕≧ࡀ᪥ᖖ⏕ά࡟ᨭ㞀ࢆࡁࡓࡍ࠿࡝࠺࠿࡛ PMS
ࡢ᭷↓ࢆุ᩿ࡋࡓࠋ෭࠼⑕ࡢ௜㝶⑕≧ࡣࠊ୕ᾆࡽ 11)ࡢᩥ⊩ࢆཧ⪃࡟㡯┠ࢆỴᐃࡋࠊࡑࡢ⛬ᗘࢆ⑕≧ࡀ
࡞࠸࣭㍍ᗘ࣭㔜ᗘࡢ 3 ẁ㝵࡟ศ㢮ࡋࡓࠋ᭶⤒ᅔ㞴⑕ࡣࠊୗ⭡㒊③ࡸ⭜③࡞࡝ࡢ᭶⤒③ࡢ࡯࠿ࠊ㢌③ࠊ
⭡㒊⭾‶ឤࠊ჎Ẽࠊ჎ྤࠊ⬺ຊឤࠊ඲㌟೏ᛰឤࠊࡵࡲ࠸ࠊ㣗ḧ୙᣺ࠊୗ⑩ࠊ࠸ࡽ࠸ࡽࠊᢚ࠺ࡘ࡞࡝ࡀ
Ꮡᅾࡋࠊࡑࡢ⑕≧ࡀ᪥ᖖ⏕ά࡟ᨭ㞀ࢆࡁࡓࡍࡶࡢ࡜ࡋࡓ
12)
ࠋᛶ࿘ᮇࡣࠊ25ࠥ38 ᪥࿘ᮇୟࡘࡑࡢኚື
ࡀ 6 ᪥௨ෆࢆつ๎ⓗ࡜ࡋࠊᛶ࿘ᮇࡀ 24 ᪥௨ୗ࠶ࡿ࠸ࡣ 39 ᪥௨ୖࠊኚືࡀ 7 ᪥௨ୖࡢ࠸ࡎࢀ࠿ࡢሙྜ
ࢆ୙つ๎ࠊᛶ࿘ᮇ࠶ࡿ࠸ࡣኚືࡢ࠸ࡎࢀ࠿ࡀศ࠿ࡽ࡞࠿ࡗࡓሙྜࢆ୙᫂࡜ࡋࡓࠋࡲࡓࠊ᭱⤊᭶⤒࡞ࡽ
ࡧ࡟᭶⤒࿘ᮇ࠿ࡽ༸⬊ᮇ㸦᤼༸๓㸧࡜㯤యᮇ㸦᤼༸ᚋ㸧ࢆ᥎ᐃࡋࡓࠋ
㸦2㸧⮬ᚊ⚄⤒άືᗘࡢホ౯
⮬ᚊ⚄⤒άືᗘࡣࠊ෭Ỉ㈇Ⲵࢸࢫࢺ࡞ࡽࡧ࡟ᚰ㟁ᅗ࿘Ἴᩘゎᯒࢆ⏝࠸࡚ホ౯ࡋࡓࠋࡑࡢ ᐃࡣ᤼༸
๓࡜᤼༸ᚋࡢ 2 ᅇࠊྛᑐ㇟⪅࡛ᐇ᪋ࡋࡓࠋ
a㸧෭Ỉ㈇Ⲵࢸࢫࢺ
ᒸ⏣ࡽ 3)ࡢ᪉ἲ࡟‽ࡌࠊ25Υs1Υࡢ㦁㡢ࡢ࡞࠸㒊ᒇ࡟ᑡ࡞ࡃ࡜ࡶ 10 ศ㛫㥆໬ࡉࡏࡓᚋࠊᕥᡭ♧ᣦ
ᮎ⠇ࡢᡭᤸഃࡢ⓶⭵ ᗘࢆ஦๓࡟ᨺᑕ ᗘィ㸦IT̾550S㸪ओᇼሙ〇సᡤ㸧࡟࡚ ᐃࡋࡓᚋࠊ4ΥࡢỈ࡟
30 ⛊㛫ᕥᡭࢆᡭ㤳ࡲ࡛ᾐₕࡋࠊࡑࡢᚋᗙ఩࡛⫝㛵⠇࠿ࡽᮎᲈ㒊ࡀỈᖹ࡟࡞ࡿࡼ࠺࡟ᮘࡢୖ࡟⭎ࢆ஌
ࡏࠊᕥᡭ♧ᣦᮎ⠇ࡢᡭᤸഃࡢ⓶⭵ ᗘࢆᨺᑕ ᗘィ࡟࡚ 1ࠥ10 ศᚋࡲ࡛㸯ศẖ࡟ ᐃࡋࡓࠋ
b㸧ᚰ㟁ᅗ࿘Ἴᩘゎᯒ
⬦ᢿཬࡧᚰ㟁ᅗ᳨ᰝ㸦࣮࢝ࢹ࢕࢜ࢫࢱ࣮FX̾7302, ࣇࢡࢲ㟁Ꮚᰴᘧ఍♫㸧࡟ࡼࡾ R̾R 㛫㝸ࢆ ᐃࡋ
ࡓ 13)ࠋR̾R 㛫㝸 ᐃࡣࠊᐊ 25Υs1Υࡢ㦁㡢ࡢ࡞࠸㒊ᒇ࡛⣙ 3 ศࡢ⮩ᗋᏳ㟼ᚋࠊ⮬↛࿧྾ୗ࡟࠾࠸
࡚ࠊᅄ⫥ㄏᑟ࡟ࡼࡾ 2 ศ㛫ᐇ᪋ࡋࡓࠋ㧗࿘Ἴᡂศ㸦High Frequency㸪௨ୗ HF㸧ࡢ⠊ᅖࢆ 0.15ࠥ0.60 ࣊
ࣝࢶ࡟ࠊప࿘Ἴᡂศ㸦Low Frequency㸪௨ୗ LF㸧ࡢ⠊ᅖࢆ 0.04ࠥ0.15 ࣊ࣝࢶ࡟タᐃࡋࠊLabview7.1 ࢆ
⏝࠸࡚࿘Ἴᩘゎᯒࢆ⾜ࡗࡓࠋLF ࡣ஺ឤ⚄⤒࡞ࡽࡧ࡟๪஺ឤ⚄⤒άືࠊHF ࡣ๪஺ឤ⚄⤒άືࠊLF/HF
ࡣ୧⪅ࡢࣂࣛࣥࢫࢆ♧ࡍᣦᶆ࡜ࡋࡓࠋ࿧྾ࡀ࿘Ἴᩘゎᯒ࡟ཬࡰࡍᙳ㡪ࢆ⪃ᰝࡋࠊHF3000ms2 ᮍ‶ࡢ 27
ྡࡢ࿘Ἴᩘゎᯒࢆ⾜ࡗࡓࠋ
3㸧⤫ィᏛⓗศᯒ
ࢹ࣮ࢱࡢ㞟ィ࣭ゎᯒ࡟ࡣ⤫ィࢯࣇࢺ Microsoft Office Excel ࢆ⏝࠸ࠊt ᳨ᐃࠊȮ஧஌᳨ᐃࢆ⾜࠸ࠊ᭷
ពỈ‽ࡣ p㸺0.05 ࡜ࡋࡓࠋ
4㸧೔⌮ⓗ㓄៖
ᮏ◊✲ࡣࠊ⚄ᡞ኱Ꮫಖ೺Ꮫ◊✲⛉೔⌮ᑂᰝጤဨ఍ࡢᢎㄆࢆᚓ࡚ᐇ᪋ࡋࡓࠋᑐ㇟⪅࡟ࡣ◊✲ࡢ┠ⓗ࡜
ෆᐜࠊ⮬⏤ཧຍ࡛࠶ࡿࡇ࡜ࠊ␒ྕ໬࡛ࡢࢹ࣮ࢱฎ⌮࡛ࣉࣛ࢖ࣂࢩ࣮࡟㓄៖ࡍࡿࡇ࡜ࢆ஦๓࡟ㄝ᫂ࡋࠊ
◊✲ཧຍࡢྠពࢆᚓࡓࠋ
Ϫ㸬⤖ᯝ
1㸧ᑐ㇟⪅⫼ᬒ㸦⾲ 1㸧
ᑐ㇟⪅ࡢᖹᆒᖺ㱋ࡣ 21.5±2.7㸦18ࠥ34㸧ṓ࡛࠶ࡗࡓࠋᖹᆒ BMI ࡣ 21±2.4㸦15.8ࠥ26.7㸧ࠊᛶ࿘ᮇࡀ
㪉
⚄኱㝔ಖ೺⣖せ
ⱝᖺዪᛶࡢ෭࠼⑕࡞ࡽࡧ࡟᭶⤒㝶క⑕≧࡬ࡢ⮬ᚊ⚄⤒άືᗘࡢ㛵ࢃࡾ
つ๎ⓗ 34 ྡ㸦68㸣㸧ࠊ୙つ๎ 9 ྡ㸦18㸣㸧ࠊ୙᫂ 7 ྡ㸦14㸣㸧࡛࠶ࡗࡓࠋ⌧ᅾႚ↮ࡋ࡚࠸ࡿࡶࡢࡣ࠸
࡞࠿ࡗࡓࠋ෭࠼⑕ࡢ࠶ࡿࡶࡢࡣ 22 ྡ㸦44㸣㸧ࠊPMS ࡣ 15 ྡ㸦30㸣㸧࡛࠶ࡗࡓࠋ
⾲ 1 ᑐ㇟⪅ࡢ⫼ᬒ㸦N=50㸧
ᖺ㱋㸦ṓ㸧
21.5s2.7㸦Max34㸪min18㸧
BMI㸦kg/m2㸧
21s2.4㸦Max26.7㸪min15.8㸧
ᛶ࿘ᮇ
つ๎ⓗ 34㸦68%㸧
୙つ๎ 9㸦18%㸧
୙᫂ 7㸦14%㸧
෭࠼⑕
࠶ࡾ 22㸦44%㸧
࡞ࡋ 28㸦56%㸧
PMS
࠶ࡾ 15㸦30%㸧
࡞ࡋ 35㸦70㸣㸧
᭶⤒ᅔ㞴⑕
࠶ࡾ 15㸦30%㸧
࡞ࡋ 35㸦70%㸧
❧ࡕࡃࡽࡳ
㔜ᗘ࠶ࡾ 3㸦6%㸧
㍍ᗘ࠶ࡾ 28㸦56%㸧
࡞ࡋ 19㸦38%㸧
ࡵࡲ࠸
㔜ᗘ࠶ࡾ 2㸦4%㸧
㍍ᗘ࠶ࡾ 10㸦20%㸧
࡞ࡋ 38㸦76%㸧
2㸧෭࠼⑕࡜⑓ⓗ᭶⤒㝶క⑕≧㸦⾲ 2㸧
෭࠼⑕⩌࡛ࡣ㠀෭࠼⑕⩌࡟ẚࡋ࡚ࠊ᭶⤒ᅔ㞴⑕ࠊPMSࠊ㍍࠸ࡵࡲ࠸ࠊ㍍࠸⫪ࡇࡾࢆ᭷ࡍࡿ๭ྜࡀ᭷
ព࡟ከ࠿ࡗࡓࠋBMI ࡣ෭࠼⑕⩌ࡢ᪉ࡀప್ࢆ࡜ࡿഴྥ࡟࠶ࡾࠊ㍍࠸❧ࡕࡃࡽࡳࡶ෭࠼⑕⩌ࡢ᪉ࡀከ࠸
ഴྥ࡟࠶ࡗࡓࠋ୙╀ࠊ౽⛎ࠊ㢌③ࠊ㔜ᗘࡢ❧ࡕࡃࡽࡳࠊ㔜ᗘࡢ⫪ࡇࡾࠊ㔜ᗘࡢࡵࡲ࠸ࠊᛶ࿘ᮇࡢつ๎
ᛶࡢ๭ྜ࡟ࡘ࠸࡚ࡣ୧⩌㛫࡟᭷ពᕪࡣ࡞࠿ࡗࡓࠋ
⾲ 2 ෭࠼⑕ࡢ᭷↓࡛ 2 ⩌ศࡅࡋࡓሙྜࡢ୙ᐃឋッࡢ๭ྜẚ㍑㸦*㸸p㸺0.05㸪**㸸p㸺0.01㸧
෭࠼⑕⩌㸦n=22㸧
㠀෭࠼⑕⩌㸦n=28㸧
p್
BMI㸦kg/m2㸧
20.3s2.5
21.5s2.7
n.p
᭶⤒ᅔ㞴⑕
࠶ࡾ
11㸦50.0%㸧
4㸦14.3%㸧
*
PMS ࠶ࡾ
9㸦40.9%㸧
6㸦21.4%㸧
**
6㸦27.3%㸧
4㸦14.3%㸧
*
13㸦59.1%㸧
11㸦39.3%㸧
**
14㸦63.6%㸧
14㸦50.0%㸧
n.p
つ๎ⓗ 14
㸦63.6%㸧
つ๎ⓗ 20
㸦71.4%㸧
n.p
㍍࠸ࡵࡲ࠸
࠶ࡾ
㍍࠸⫪ࡇࡾ
࠶ࡾ
㍍࠸❧ࡕ
ࡃࡽࡳ࠶ࡾ
ᛶ࿘ᮇࡢ
つ๎ᛶ
3㸧෭࠼⑕࣭᭶⤒㝶క⑕≧࡜⮬ᚊ⚄⤒άືᗘ
a㸧෭Ỉ㈇Ⲵࢸࢫࢺ㸦ᅗ 1ࠊ2㸧
ᛶ࿘ᮇࡀつ๎ⓗ࡛᤼༸๓ᚋࡀุ᩿࡛ࡁࡿ 34 ྡࡢࢹ࣮ࢱࢆ⏝࠸ศᯒࡋࡓࠋ
෭࠼⑕⩌࡛ࡣ㠀෭࠼⑕⩌࡟ẚࡋ࡚ࠊ᤼༸๓࡛ࡣࠊ෭Ỉ㈇Ⲵ๓್㸦29.3s2.4Υࠊ31.5s2.1Υࠊp㸺0.01㸧ࠊ
2 ศᚋ್㸦20.1s3.7Υࠊ23.9s5.2Υࠊp㸺0.05㸧ࠊ3 ศᚋ್㸦21.3s4.3Υࠊ27.3s5.6Υࠊp㸺0.01㸧ࠊ4 ศ
ᚋ್㸦22.3s5.3Υࠊ28.1s5.2Υࠊp㸺0.01㸧ࠊ5 ศᚋ್㸦22.6s5.5Υࠊ28.8s5.1Υࠊp㸺0.01㸧ࠊ6 ศᚋ್
㸦24.1s5.9Υࠊ29.0s5.2Υࠊp㸺0.05㸧ࠊ7 ศᚋ್㸦25.1s6.03Υࠊ29.1s5.2Υࠊp㸺0.05㸧࡛᭷ព࡟ప
್ࢆ♧ࡋࡓࠋ୍᪉ࠊ᤼༸ᚋ࡛ࡣ 6 ศᚋ್㸦24.7s6.3Υࠊ28.8s4.6Υࠊp㸺0.05㸧ࠊ7 ศᚋ್㸦25.2s6.4Υࠊ
29.2s4.3Υࠊp㸺0.05㸧ࠊ8 ศᚋ್㸦25.4s6.4Υࠊ29.3s4.2Υࠊp㸺0.05㸧ࠊ9 ศᚋ್㸦25.4s6.3Υࠊ30.0
㪊
୕ᾆ ᩥᏊ ௚
s3.9Υࠊp㸺0.05㸧ࠊ10 ศᚋ್㸦25.5s5.8Υࠊ30.1s3.6Υࠊp㸺0.01㸧࡛ࠊ෭࠼⑕⩌࡟࠾࠸࡚᭷ព࡟ప
್ࡀほᐹࡉࢀࡓࠋ
᤼༸๓ᚋྛᮇ࡟࠾ࡅࡿ PMS ⩌࡜㠀 PMS ⩌࡟࠾ࡅࡿẚ㍑࡛ࡣࠊ᤼༸๓࡛ࡣ 7 ศᚋ್㸦24.9s6.8Υࠊ
28.5s5.2Υ㸧࠾ࡼࡧ 8 ศᚋ್㸦25.1s6.3Υࠊ28.9s5.0Υ㸧࡟࠾࠸࡚ PMS ⩌ࡀ㠀 PMS ⩌࡟ẚࡋ࡚ప್
ࢆ࡜ࡿഴྥࢆ♧ࡋࡓࡀ᭷ព࡞ᕪࡣほᐹࡉࢀ࡞࠿ࡗࡓࠋ᤼༸ᚋ࡛ࡣ୧⩌㛫࡟᭷ព࡞ᕪࡣࡳࡽࢀ࡞࠿ࡗࡓࠋ
ᅗ 1 ෭࠼⑕⩌ཬࡧ㠀෭࠼⑕⩌ࡢ᤼༸๓ᚋྛᮇ࡟࠾ࡅࡿ෭Ỉ㈇Ⲵᐇ㦂ࡢ⤖ᯝ
㸦A㸸᤼༸๓㸪B㸸᤼༸ᚋ㸧
㸦*㸸p㸺0.05㸪**㸸p㸺0.01㸧
A
B
ᅗ 2 PMS ⩌ཬࡧ㠀 PMS ⩌ࡢ᤼༸๓ᚋྛᮇ࡟࠾ࡅࡿ෭Ỉ㈇Ⲵᐇ㦂ࡢ⤖ᯝ
㸦A㸸᤼༸๓㸪B㸸᤼༸ᚋ㸧
A
B
b㸧ᚰ㟁ᅗ࿘Ἴᩘゎᯒ㸦⾲ 3㸧
෭࠼⑕⩌ࡢ LF/HF ẚࡣ᤼༸๓ 1.06s1.21ࠊ᤼༸ᚋ 1.36s1.75ࠊ㠀෭࠼⑕⩌࡛ࡣ᤼༸๓ 0.97s0.78ࠊ
᤼༸ᚋ 0.96s1.32 ࡛࠶ࡗࡓࠋPMS ⩌ࡢ LF/HF ẚࡣ᤼༸๓ 0.95s0.69ࠊ᤼༸ᚋ 1.66s2.10ࠊ㠀 PMS ⩌
ࡢ LF/HF ẚࡣ᤼༸๓ 1.03s1.06ࠊ᤼༸ᚋ 0.93s1.20 ࡛࠶ࡗࡓࠋ᭶⤒ᅔ㞴⑕⩌ࡢ LF/HF ẚࡣ᤼༸๓ 0.99
s0.89ࠊ᤼༸ᚋ 2.47s2.48ࠊ㠀᭶⤒ᅔ㞴⑕⩌ࡢ LF/HF ẚࡣ᤼༸๓ 1.01s1.01ࠊ᤼༸ᚋ 0.65s0.35 ࡛࠶
ࡗࡓࠋ෭࠼⑕ࠊ⑓ⓗ᭶⤒㝶క⑕≧ࢆ᭷ࡍࡿ⩌࡛ࡣ᤼༸ᚋ LF/HF ẚࡀ㧗ࡃ࡞ࡿഴྥࡀほᐹࡉࢀࡓࠋ
㪋
⚄኱㝔ಖ೺⣖せ
ⱝᖺዪᛶࡢ෭࠼⑕࡞ࡽࡧ࡟᭶⤒㝶క⑕≧࡬ࡢ⮬ᚊ⚄⤒άືᗘࡢ㛵ࢃࡾ
⾲ 3 ᚰ㟁ᅗ࿘Ἴᩘゎᯒ⤖ᯝ
㸦A㸸෭࠼⑕࡜㠀෭࠼⑕⩌㸪B㸸PMS ⩌࡜㠀 PMS ⩌㸪
C㸸᭶⤒ᅔ㞴⑕⩌࡜㠀᭶⤒ᅔ㞴⑕⩌㸧
A㸦N=27㸧
෭࠼⑕⩌㸦n=11㸧
2
2
㠀෭࠼⑕⩌㸦n=16㸧
2
LF㸦ms 㸧
HF㸦ms 㸧
LF/HF
LF㸦ms 㸧
HF㸦ms2㸧
LF/HF
᤼༸๓
709s872
822s567
1.06s1.21
736s583
998s800
0.97s0.78
᤼༸ᚋ
671s664
838s877
1.36s1.75
563s342
889s604
0.96s1.32
B㸦N=27㸧
PMS ⩌㸦n=7㸧
2
㠀 PMS ⩌㸦n=20㸧
2
2
LF㸦ms 㸧
HF㸦ms 㸧
LF/HF
LF㸦ms 㸧
HF㸦ms2㸧
LF/HF
᤼༸๓
583s337
900s772
0.95s0.69
775s801
936s700
1.03s1.06
᤼༸ᚋ
711s705
854s859
1.66s2.10
570s401
874s677
0.93s1.20
C㸦N=27㸧
᭶⤒ᅔ㞴⑕⩌㸦n=7㸧
㠀᭶⤒ᅔ㞴⑕⩌㸦n=20㸧
LF㸦ms2㸧
HF㸦ms2㸧
LF/HF
LF㸦ms2㸧
HF㸦ms2㸧
LF/HF
᤼༸๓
604s596
846s669
0.99s0.89
᤼༸ᚋ
623s400
433s270
2.47s2.48
768s748
955s734
1.01s1.01
601s533
1021s775
0.65s0.35
p=0.21
p=0.15
ϫ㸬⪃ᐹ
ᮏ◊✲࡛ࡣࠊ෭࠼⑕࡞ࡽࡧ࡟⑓ⓗ᭶⤒㝶క⑕≧࡛࠶ࡿ PMS ࡜᭶⤒ᅔ㞴⑕ࢆṇ☜࡟ᢕᥱࡋࠊᛶ࿘ᮇ
࡟క࠺⮬ᚊ⚄⤒άືᗘࢆ෭Ỉ㈇Ⲵࢸࢫࢺ࡞ࡽࡧ࡟ᚰ㟁ᅗ࿘Ἴᩘゎᯒ࡟ࡼࡾㄪ࡭ࡿࡇ࡜࡟ࡼࡾࠊ⮬ᚊ⚄
⤒άືࡢࡇࢀࡽࡢ⑓ែ⏕⌮࡬ࡢ㛵ࢃࡾࢆ᳨ウࡋࡓࠋࡑࡢ⤖ᯝࠊ෭࠼⑕ࠊPMS ࠶ࡿ࠸ࡣ᭶⤒ᅔ㞴⑕ࢆ
᭷ࡍࡿࡶࡢࡣࠊ㠀ྜే⩌࡟ẚࡋ࡚⮬ᚊ⚄⤒άືㄪ⠇ࡢపୗ࠶ࡿ࠸ࡣᨭ㞀ࢆࡁࡓࡋ࡚࠸ࡿྍ⬟ᛶࡀ࠶ࡿ
ࡇ࡜ࠊࡲࡓࠊᛶ࿘ᮇࡢ᫬ᮇ࡟ࡼࡾ⮬ᚊ⚄⤒άືㄪ⠇ࡢ⑓ែ࡬ࡢ㛵ࢃࡾ࡟┦㐪ࡀࡳࡽࢀࡿࡇ࡜ࢆ᫂ࡽ࠿
࡟ࡋࡓࠋ
෭࠼ࡢ⮬ぬࡀ࠶ࡿ⪅ࡣࠊ⫪ࡇࡾࠊ౽⛎ࠊ୙╀ࡀከ࠸࡜࠸࠺ሗ࿌ࡀ࠶ࡿ 8)ࡀࠊᮏ◊✲࡛ࡶ PMSࠊ❧ࡕ
ࡃࡽࡳࠊࡵࡲ࠸ࢆ᭷ࡍࡿሙྜࠊ෭࠼⑕ࢆྜేࡋ࡚࠸ࡿࡇ࡜ࡀከ࠿ࡗࡓࠋࡇࢀࡽዪᛶ≉᭷ࡢ೺ᗣ㞀ᐖࡀ
㔜」ࡍࡿࡇ࡜࠿ࡽࠊඹ㏻ࡢ⑓ែ⏕⌮࡜ࡋ࡚⮬ᚊ⚄⤒ኻㄪࡢ㛵ࢃࡾࡀᙉࡃ♧၀ࡉࢀࡿࠋ
⮬ᚊ⚄⤒άືᗘ࡞ࡽࡧ࡟ࡑࡢㄪ⠇ᶵᵓࢆ▱ࡿୖ࡛෭Ỉ㈇Ⲵࢸࢫࢺࡢ᭷⏝ᛶࡣド᫂ࡉࢀ࡚࠸ࡿ
2,14,15)
ࠋ
௒ᅇࠊ෭࠼⑕ࡢ᭷↓ู࡟෭Ỉ㈇Ⲵᚋࡢ⓶⭵ ᗘᅇ᚟ࢆᛶ࿘ᮇ࡜ࡢ㛵㐃࡛ㄪ࡭ࡓ࡜ࡇࢁࠊ෭࠼⑕⩌ࡣ᤼
༸๓ᚋ࡜ࡶ࡟㠀෭࠼⑕⩌࡟ẚࡋ࡚⓶⭵ ᗘࡢᅇ᚟ࡀᝏࡃࠊ⮬ᚊ⚄⤒ࢆ௓ࡍࡿ⓶⭵⾑⟶ᣑᙇᶵ⬟࡟ᨭ㞀
ࢆࡁࡓࡋ࡚࠸ࡿྍ⬟ᛶࡀ♧၀ࡉࢀࡓࠋࡲࡓࠊ෭࠼⑕⩌ࡣ᤼༸๓࡛ࡣ㈇Ⲵ┤ᚋᩘศ㛫ࡢ⓶⭵ ᗘࡢᅇ᚟
ࡀᝏ࠸ࡶࡢࡢ᫬㛫ࡢ⤒㐣࡜࡜ࡶ࡟ᚎࠎ࡟ᅇ᚟ࡍࡿഴྥࡀ࠶ࡿ୍᪉ࠊ᤼༸ᚋ࡛ࡣ᫬㛫ࡀ⤒㐣ࡋ࡚ࡶ⓶⭵
ᗘࡢᅇ᚟࡟㐜ᘏࡀࡳࡽࢀࡓࠋ᤼༸๓ᚋ࡛ᅇ᚟㐣⛬࡟┦㐪ࡀࡳࡽࢀࡿࡇ࡜ࡣࠊ⮬ᚊ⚄⤒ᶵ⬟ㄪ⠇ࡀ᤼
༸๓࡟ẚࡋ࡚᤼༸ᚋ࡟ࡼࡾపୗࡋ࡚࠸ࡿࡇ࡜ࡀ᥎ᐹࡉࢀࡿࠋྠᵝ࡟ PMS ࡟࠾࠸࡚ࡶࠊ᤼༸๓࡟࠾࠸
࡚ࡣ㈇Ⲵᚋᩘศ࡛ PMS ⩌ࡀ㠀 PMS ⩌࡟ẚࡋ࡚ࡸࡸᅇ᚟ࡀᝏࡃࠊ᤼༸ᚋ࡛ࡣ㈇Ⲵᚋࡢᅇ᚟ࡀ㐜ᘏࡍࡿ
ഴྥࡀほᐹࡉࢀࡓࠋ
ᛶ࿘ᮇ࡜⮬ᚊ⚄⤒࿘Ἴᩘゎᯒ࡟㛵ࡋ࡚ࠊṇᖖ࡞᭶⤒࿘ᮇࡢሙྜ HF ࡣ༸⬊ᮇ࡟㧗ࡃࠊLF/HF ࡣ㯤య
ᮇ࡟㧗ࡃ࡞ࡿࡇ࡜ࡀሗ࿌ࡉࢀ࡚࠸ࡿ
16)
ࠋࡲࡓࠊPMS ࢆ᭷ࡍࡿ⪅ࡣ༸⬊ᮇࡼࡾࡶ㯤యᚋᮇ࡛඲⮬ᚊ⚄
㪌
୕ᾆ ᩥᏊ ௚
⤒άື࡜ HF ࡀ᭷ព࡟ప࠿ࡗࡓࡇ࡜ࡀ♧ࡉࢀ࡚࠸ࡿ 6,7)ࠋ௒ᅇᡃࠎࡢᚰ㟁ᅗ࡟ࡼࡿ⮬ᚊ⚄⤒࿘Ἴᩘゎᯒ
࡛ࡣࠊ᤼༸๓ᚋ࡛᭷ពᕪࡣ࡞࠿ࡗࡓࡶࡢࡢࠊPMS ⩌࡟࠾࠸࡚ HF ࡀ᤼༸ᚋ࡛ప್ࢆ♧ࡋࠊࡲࡓࠊ෭࠼
⑕⩌ࡸ PMS ⩌࡛᤼༸ᚋ࡟ LF/HF ࡀ㧗್ࢆ♧ࡋࡓࠋࡇࡢࡇ࡜࠿ࡽࠊ෭࠼⑕⩌ࡸ PMS ⩌ࡣ᤼༸ᚋ࡟஺ឤ
⚄⤒ࡀࡸࡸඃ఩࡟࡞ࡗ࡚࠾ࡾࠊࡇࡢࡇ࡜ࡀ⓶⭵⾑⟶ࡢᣑᙇᶵ⬟ࡢᨭ㞀࡟ࡘ࡞ࡀࡗ࡚࠸ࡿࡇ࡜ࡀ⪃࠼ࡽ
ࢀࡿ 9)ࠋ෭࠼⑕ࡸ⑓ⓗ᭶⤒㝶క⑕≧ࡢ⑓ែ⏕⌮࡬ࡢ⮬ᚊ⚄⤒άືᗘࡢ㛵ࢃࡾࡣ኱ࡁࡃࠊࡑࡢㄪ⠇ᶵᵓ
ࡢᨭ㞀ࡣ୧⪅ࡢ⑓ែᙧᡂࡢඹ㏻ᇶ┙࡛࠶ࡿྍ⬟ᛶࡀ♧၀ࡉࢀࡿࠋ
෭࠼⑕࡟ᑐࡋ࡚ࠊ⏕ά⩦័ࡢᨵၿ࡜࡜ࡶ࡟⸆≀⒪ἲ࡜ࡋ࡚ࠊᚠ⎔ᨵၿ๣ࠊ₎᪉〇๣➼ࠊࡲࡓ⏕ጧࡸ
࣮ࣟࣖࣝࢮ࣮ࣜ➼ࡢ᭷ຠᛶࡶሗ࿌ࡉࢀ࡚࠸ࡿ
2,17,18,19)
ࠋ୍᪉ࠊ⑓ⓗ᭶⤒㝶క⑕≧࡟ᑐࡋ࡚ࡣࠊPMS ࡛
ࡣࣆࣝࠊྥ⢭⚄⸆ࡸ࢝ࣝࢩ࣒࢘〇๣ࠊ
᭶⤒ᅔ㞴⑕࡛ࡣ㙠③๣ࡸࣆࣝ➼ࡢ᭷⏝ᛶࡀ♧ࡉࢀ࡚࠸ࡿ 20,21,22)ࠋ
ࡇࢀࡽ⸆≀⒪ἲࡢ᭷⏝ᛶࢆ⑓ⓗ⏕⌮ࡢほⅬ࠿ࡽホ౯ࡍࡿࡓࡵ࡟ࡣࠊ἞⒪๓ᚋࡢ⮬ᚊ⚄⤒άືᗘࢆㄪ࡭
ࡿࡇ࡜ࡀ኱ษ࡛࠶ࡿࠋ෭࠼⑕ࡸ⑓ⓗ᭶⤒㝶క⑕≧ࡣ㔜」ࡍࡿࡇ࡜ࡶከࡃࠊዪᛶࡢ QOL ࢆⴭࡋࡃపୗ
ࡉࡏࡿࠋࡑࡢ⑓ែ⏕⌮ࡢ᰿ᖿࢆ࡞ࡍ⮬ᚊ⚄⤒άືᗘ࡜ࡑࡢㄪ⠇ᶵ⬟ࢆྥୖࡉࡏࡿࡼ࠺࡞⮬ᚊカ⦎ἲ➼
ࡢಖ೺ᣦᑟࡶ኱ษ࡛࠶ࡿ࡜⪃࠼ࡽࢀࡿࠋ
ᩥ⊩
1.
Elsi Dwi Hapsari,Yuria Mantani,Hiroya Matsuo.The Prevalence of Premenstrual and Its
Modulation by Lifestyle and Psychological Factors in High Scool Students.Bulletin of
Health Sciences Kobe,22,2006.
2.
3.
ᯇᑿ༤ဢ.෭࠼ᛶ࡜₎᪉.⏘፬ே⛉἞⒪,82(3):329̾332,2001.
ᒸ⏣╬⨾,Ᏹ㔝඘Ꮚ,Ọ㔝ⱥᏊ,㔝ᮧ⩏἞,኱ᖹဴஓ,బ⸨┾୍,ᔱᮏ ႛ.෭࠼ᛶ࡟࠾ࡅࡿ෭Ỉ㈇Ⲵࢧ
࣮ࣔࢢࣛࣇ࢕࡜ᚠ⎔ჾ᳨デᡂ⦼,⏕ά⩦័࡜ࡢ㛵㐃.Biomedical Thermology.24(3):44̾50,2006.
4.
㧗ᮌ⤢ຍ, ᒣཱྀගᯞ, ⬥ᆏࡋ࠾ࡾ, ᆏ᰿┤ᶞ, ᳃㇂ᩄኵ, Ọ஭ᡂ⨾㸬ⱝᖺዪᛶࡢ෭࠼ឤ࡟ཬࡰࡍ࢚
ࢿࣝࢠ࣮ᦤྲྀ㔞,ࢲ࢖࢚ࢵࢺ,࠾ࡼࡧయ⇕⏘⏕ไᚚ࡟㛵ࢃࡿ஺ឤ⚄⤒άືࡢᙳ㡪.⫧‶◊
✲,17(2):119̾126,2011.
5.
ཎ⏣㔛ዉ,ᶫᮏ⨾㈗ᜨ,Ἔᮌ⿱Ꮚ,༓ⴥᖾᏊ,ᕝᾉ຾ᘯ,㧗ᶫ᠇୍.᭶⤒๓⑕ೃ⩌࡜᭶⤒ᅔ㞴⑕࡟ࡘ࠸
࡚.ᮾὒ⒪ἲᏛᰯ༠఍Ꮫ఍ㄅ,34:133̾137,2011.
6.
ᯇᮏ⌔ᕼ,ᚋᒣᑦஂ,ᮌᮧဴஓ,ᯘ 㐩ஓ,᳃㇂ᩄኵ.᭶⤒๓⑕ೃ⩌࣭᭶⤒๓୙ᛌẼศ㞀ᐖࡢⓎ⑕࡜⮬
ᚊ⚄⤒άືືែ࡜ࡢ㛵㐃.⏘፬ே⛉἞⒪,95(5):544̾553,2007.
7.
Baker FC, Colrain IM, Trinder J.Reduced parasympathetic activity during sleep in the
symptomatic phase of severe premenstrual syndrome.J Psychosom Res,65(1):13̾22,2008.
8.
ᑎ⃝ᤩᖺ:₎᪉་Ꮫ࡟࠾ࡅࡿ෭࠼⑕ࡢㄆ㆑࡜ࡑࡢ἞⒪.⏕⸆Ꮫ:85̾96,1987.
9.
ⓑᅵ࡞࡯Ꮚ,㛗ሯṇ᫭,༓ⴥ ༤,ᮌᮧṊᙪ,ᒸ஭ ᓫ.ⱝᖺ⪅ࡢ᭶⤒๓⑕ೃ⩌.⏘፬ே⛉἞
⒪,91(5):516̾522,2005.
10. JF Mortola,MD L Girton PhD,L Beck PhD and SSC Yen MD.Diagnosis of premenstrual
syndrome by a simple,prospective,and reliable instrument.the calendar of premenstrual
experiences,302̾307,1990.
11. ୕ᾆ཭⨾,஺㔝ዲᏊ,ఫᮏ࿴༤,㔠ᒣᑦ⿱.㟷ᖺᮇዪᏊࡢࠕ෭࠼ࠖࡢ⮬ぬ࡜ࡑࡢせᅉ࡟㛵ࡍࡿ◊✲.ẕ
ᛶ⾨⏕,42(4):784̾789,2001.
12. ⚟⃝⣲Ꮚ.⑕≧࣭⑕ೃ࡟ᑐࡍࡿ₎᪉἞⒪,᭶⤒ᅔ㞴⑕࣭᭶⤒๓⑕ೃ⩌.デ᩿࡜἞⒪,97(8):1616̾
1619,2009.
13. ➉ᯘ᱇Ꮚ,ᯇᑿ༤ဢ.ࡘࢃࡾࡢ᥎⛣࡞ࡽࡧ࡟㔜⑕ᗘ࡜⮬ᚊ⚄⤒άືᗘ࡜ࡢ㛵㐃.⚄኱㝔ಖ೺⣖
せ,2010.
14. ྂụಖ㞝,ᱜ஭ಙኵ,ᮡᒣ⏤ᶞ.෭Ỉ㈇Ⲵ࡟ᑐࡍࡿ⓶⭵⾑⟶཯ᛂ.⮬ᚊ⚄⤒,28(1):26̾32,1991.
㪍
⚄኱㝔ಖ೺⣖せ
ⱝᖺዪᛶࡢ෭࠼⑕࡞ࡽࡧ࡟᭶⤒㝶క⑕≧࡬ࡢ⮬ᚊ⚄⤒άືᗘࡢ㛵ࢃࡾ
15. ᴋぢ⏤㔛Ꮚ,ỤᏲ㝧Ꮚ.ᡂ⇍ᮇዪᛶࢆᑐ㇟࡜ࡋࡓ෭Ỉ㈇Ⲵヨ㦂࡟ࡼࡿ෭࠼⑕ࡢホ౯.᪥ᮏຓ⏘Ꮫ఍
ㄅ,23(2):24̾250,2009.
16. ᯇᮏె㑣Ꮚ,ᯇ⏣ᫀᏊ,ᐑ⏣ᐩ⨾,၈ᵽࡉࡸ㤶,ᕷཎΎᚿ,ᖹ㔝 ᆒ.㧗↷ᗘග↷ᑕ⒪ἲ࡟ࡼࡿ᭶⤒࿘
ᮇࡢ⮬ᚊ⚄⤒ᶵ⬟ࡢኚ໬.ᒣཱྀ་Ꮫ,55(5):167̾172,2006.
17. ᒣ⏣඾Ꮚ,ྜྷᮧ⿱அ.ⱝᖺዪᛶࡢ෭࠼⑕࡟ᑐࡍࡿ࣮ࣟࣖࣝࢮ࣮ࣜᦤྲྀࡢᨵၿຠᯝ.᪥ᮏᰤ㣴࣭㣗⣊Ꮫ
఍ㄅ➨ 63(6):271̾278,2010.
18. ኟ㔝㇏ᶞ,ᖹᰗ せ.⏕ጧᢳฟ≀ࡢ⤒␎ᦤྲྀࡀ෭࠼ᛶࡢேࡢ࢚ࢿࣝࢠ࣮ᾘ㈝➼࡟ཬࡰࡍຠᯝ.ே㛫
ᕤᏛ,45(4):236̾241,2009.
19. Ᏻ⏣(ᒣୗ)ளᕼᏊ,ᐃΎ ๛,୕㰘ோᚿ,ஂಖ⏣೔ኵ.⢾㌿⛣࣊ࢫ࣌ࣜࢪࣥࡢ⤒ཱྀᦤྲྀ࡟ࡼࡿ෭࠼⑕
࡞ࡽࡧ࡟㛵㐃ࡍࡿ୙ᐃឋッࡢᨵၿຠᯝ.᪥ᮏᮍ⑓ࢩࢫࢸ࣒Ꮫ఍㞧ㄅ,16(1):6̾16,2010.
20. ኴ⏣༤Ꮥ.፬ே⛉་⒪࡜ࡇࢀ࠿ࡽࡢ₎᪉⒪ἲ,෭࠼⑕࡜₎᪉⸆.⏘፬ே⛉἞⒪,98(1):47̾50,2009.
21. Thys-Jacobs S.Micronutrients and the premenstrual syndrome: the case for calcium㸬J Am
Coll Nutr,19(2):220̾7,2000.
22. ᑠ⏣⍞ᜨ᭶⤒࡟㛵ࡍࡿ࠿ࡽࡔࡢ୙ㄪ̾᭶⤒③̾ࢹࣥࢱࣝࣁ࢖ࢪ࣮ࣥ29(3):342̾344,2009.
㪎
୕ᾆ ᩥᏊ ௚
The modulation of Hiesho and menstruation related symptoms by
autonomic nerve activity in Japanese young women
Fumiko Miura1, Kaori Nakai1, Hiroya Matsuo2
Abstract
The purposes of this study were to investigate the pathosis of Hiesho and menstruation related symptoms in
Japanese young women and identify the modulation by autonomic nerve activity to their pathophysiology.
Self-reported questionnaires, which have included student’s background, menstruation, diagnosis criteria of
Hiesho and Premenstrual Syndrome (PMS), lifestyle factors, were delivered to 50 Kobe University Nursing
students. Cold water loading test and spectral heart rate variability analysis were performed in the proliferative
and secretory phase of menstruation cycle to evaluate the autonomic nerve activity. There were significant
differences in the recovery of skin temperature after loading the cold water between Hiesho group and healthy
group, especially in the secretory phase of menstruation cycle. HF tended to be higher in PMS group than
healthy group and LF/HF tended to be higher in Hiesho and PMS group than Healthy group, in the secretory
phase of menstruation, respectively. It was suggested that the dysfunction of autonomic nerve activity was
associated with the pathophysiology of Hiesho and PMS, had the differences in its severity between
proliferative and secretory phase of menstrual cycle.
Key Words: Hiesho, Premenstrual syndrome, Autonomic nerve activity, Cold water loading test, Spectral heart
rate variability
1
2
Department of Nursing, Faculty of Health Sciences, Kobe University School of Medicine
Department of International Health, Kobe University Graduate School of Health Sciences
㪏
⚄኱㝔ಖ೺⣖せ
Fly UP