ヒト器官形成期の視覚器の位置の移動について The

Photon Factory Activity Report 2015 #33(2016) B
BL-14C/2015G574
The movement of visual organs during craniofacial development
*
, 606-8507
Human Health Science, Graduate School of Medicine, Kyoto University,
53 Sakyo-ku Shogoin-Kawahara-cyo, Kyoto, 606-8507, Japan
53
1
38
8
9
2
(E986)
[1]
3
[2]
2, 3
(Carnegie Stage(CS))
CS16
23
17
[3]
CS16(2
CS10
CS17(4
[4-6]
)
)
CS17
2
CS18
3
°
[4,5]
[6]
X
i)
CT
CRL
LB
LA
4A
B/A
MRI
4B
CRL
(
R2=0.96,0.97)
LB/LA
1
CS16
2
65
MRIdata
39
CTdata
[7-9]
26
1.2
0.5
ii)
°
CS16~CS23
CRL34 ~152
CTdata
(
)
[10-12]
MRIdata
7T MR system
(BioSpec 70/20 USR; Bruker Biospin MRI, Germany)
MRI
[13]
B
Amira software version 5.5.0 (Visage Imaging; Berlin,
Germany)
0.4
CRL30
X
C
CS16 (2
)
C
4
(C
CS17 (6
)
) 2
(C
)
CS18
(
20
C
30
C
)
CS18
CRL50
Factory Activity Report 2015 #33(2016) B
(CS23)(A),
CT
CS16
CS17
2
[14,15]
(CS22)(B)
CS18
Factory Activity Report 2015 #33(2016) B
(B)
y=0.2664x+0.2458
R²=0.95537
1
LA
(LB/LA)
(mm)
(A) 40
LB
20
0.5
y=0.1142x+2.3339
R²=0.96812
0
0
0
50
100
0
150
50
CRL(mm)
4 CRL
LA(
)
100
150
200
CRL(mm)
LB(A)(
)
(B)
10
CRL(mm)
0
0
50
100
150
-10
-20
-30
-40
(A)
(B)
(mm)
10
180
y=0.0676x-0.2364
R²=0.95126
∠D
5
90
0
0
50
100
CRL(mm)
150
0
0
50
100
CRL (mm)
150
Photon Factory Activity Report 2015 #32 (2015) B
iii)
CRL
LD
D
CRL
10A
10B
LD
D
CS16
CRL50
60
80
4
CRL50mm
[15-17]
CS17
[17,18]
CT
MRI
CS16
CT