ｦｫｹ ｵ ｵ､砂уｰ環插垪ﾁｦｸ・垪ﾉ ｰﾃｦ ﾄ悄ｼo枴ｪ・ﾃ｡ｦ寛ｵ ｫ oｵ葛､ｼ ｴ

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抡¥µµ¨¡¦³¤Š„»‘Á„¨oµ nªŠže 2545
Prevalence of Pathogenic Bacteria in Acute Maxillary Sinusitis at Phramongkutkloa
Hospital in Year 2002.
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š‡´—¥n°
ᦊ°µ„µ«…oµŠ‹¤¼„°´„Á­ ( Sinusitis ) Áž}œÃ¦‡¦³šµŠÁ—·œ®µ¥Ä‹š¸É¡Å—on°¥ ×¥
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‹ÎµÁž}œ ¨³ °µ‹šÎµÄ®oÁ„·—ž{®µÁºÊ°—º°Ê ¥µÄœ£µ¥®¨´ŠÅ—o „µ¦ª·‹¥´ ‡¦´ÊŠœ¸Ê‹¹Š˜o°Š„µ¦«¹„¬µ‡ªµ¤»„
…°ŠÁºÊ°Â‡š¸Á¦¸¥„n°Ã¦‡ Sinusitis ¨³ „µ¦­¦oµŠÁ°œÅŽ¤r E - lactamase …°ŠÁºÊ°—´Š„¨nµª
ª·›¸„µ¦š—¨°Š: ×¥œÎµ­·ÉŠ­nŠ˜¦ª‹Ž¹ÉŠÁž}œ…°ŠÁ®¨ª‹µ„ᦊ°µ„µ«…oµŠ‹¤¼„…°ŠŸ¼ožiª¥ Sinusitis
ÁŒ¸¥¡¨´œ š¸Éŗo¦´„µ¦ª·œ·‹Œ´¥Ä®oŗo¦´ „µ¦Á‹µ³¨oµŠÃ¡¦Š°µ„µ«…oµŠ‹¤¼„ – „°ŠÃ­˜ «° œµ­·„
„¦¦¤ 抡¥µµ¨¡¦³¤Š„»‘Á„¨oµ ˜´ÊŠÂ˜n Á—º°œ ¤¸.‡.45 – ¡.‡.45 ‹Îµœªœ 20 ¦µ¥ ¤µšÎµ„µ¦Á¡µ³Â¥„
œ·—…°ŠÁºÊ°Â‡š¸Á¦¸¥š¸É„n°Ã¦‡ ¨³š—­°„µ¦­¦oµŠÁ°œÅŽ¤r E - lactamase …°ŠÁºÊ°š¸É¡Ã—¥ª·›¸
Chromogenic cephalosporin analog 87/312
Ÿ¨„µ¦ª·‹´¥: ¡ªnµ ˜´ª°¥nµŠš¸ÉÁ„ȝŗoš´ÊŠ®¤— 20 ¦µ¥ ¡ÁºÊ°„n°Ã¦‡ 19 ˜´ª š¸É¡¤µ„š¸É­»— ‡º°
Haemophilus influenzae ‹Îµœªœ 8 ¦µ¥ ‡·—Áž}œ 42.1 % ¦°Š¨Š¤µ ‡º° Klebsiella pneumoniae
‹Îµœªœ 3 ¦µ¥ ‡·—Áž}œ 15.79 % ¦°Š°´œ—´­µ¤ ‡º° Citrobacter sp. ‹Îµœªœ 2 ¦µ¥ ‡·—Áž}œ 10.5 %
¨³Å¤n¡ÁºÊ°Â‡š¸Á¦¸¥š¸ÉŤnčo°°„Ž·Á‹œÁ¨¥ œ°„‹µ„œ¸¥Ê ´Š¡ÁºÊ°š¸É­¦oµŠÁ°œÅŽ¤r E - lactamase 3
˜´ª ŗo„n H. influenzae , Moraxella catarrhalis ¨³ Staphylococcus aureus ‡·—Áž}œ 30 % …°Š
ÁºÊ°š¸Éš—­°„µ¦­¦oµŠÁ°œÅŽ¤r E - lactamase
„µ¦°£·ž¦µ¥Â¨³­¦»ž: ÁºÊ°š¸É­¦oµŠÁ°œÅŽ¤r E - lactamase 3 ˜´ª ŗo„n H. influenzae , Moraxella
catarrhalis ¨³ Staphylococcus aureus ‡·—Áž}œ 30 % …°ŠÁºÊ°š¸Éš—­°„µ¦­¦oµŠÁ°œÅŽ¤r E lactamase Áž°¦rÁŽœ˜r…°ŠÁºÊ°š¸ÉÂ¥„Å—o‡°n œ…oµŠ˜Éε ‹¹Š°µ‹Áž}œÂœªšµŠÄ®o¡š¥rÁ¨º°„čo¥µš¸É¤¸§š›·Í
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Á„·œÅžÁœºÉ°Š‹µ„ …o°‹Îµ„´—Äœ„µ¦Á‹µ³¨oµŠÃ¡¦Š°µ„µ«…oµŠ‹¤¼„¤¸°¥¼n¤µ„ ¨³šÎµ„µ¦«¹„¬µÄœnªŠ§—¼
¦o°œ Ž¹ÉŠŸ¼ožiª¥¤´„Ťn¤¸°µ„µ¦¦»œÂ¦Š‹œ„¦³š´ÉŠ˜o°Š¤µ¡Â¡š¥r
Á°„­µ¦°oµŠ°·Š:
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Abstract
Sinusitis is commonly found as a respiratory disease, especially caused by abcterial
infection. In initial treatment, a doctor usually prescribes anfibiotics that can affect all
of E-lactamase producing bacteria. However this practice is both a waste ful expense
and causes microorganisms to be resistant. In this study, we wanted to study the
prevalence of the pathogenic bacteria in sinusitis and E-lactamase producing bacteria.
Methods and Materials:
The specimens, fluid from the maxillary aspiration of 20 acute sinusitis patients at
Phramongkutklao hospital during March-April 2002, were sent to the microbiology
labolatory for aerobic and anaerobic culture. E-lactamase activity was determined by
the cephalosporin analog 87/312 method.
Result and Discussion;
In this study, 9 pathogenic bacteria were found from 20 specimens. The predominant
isolates were Haemophilus influenzae (8 isolates) about 42.1%, Klebsiella
pneumoniae (3 isolates) about 16.79% and Citrobacter sp. (2 isolates) about 10.5%
as well as anaerobic bacteria which was not found, We found 3 E-lactamaseproducing bacteria in about 30% of the determined bacteria, that were Haemophilus
influenzae, Moraxella catarrhalis and Staphylococcus aureus. This result is rather
low, therefore it may be a guideline for doctors to select a narrow-spectrum
antibiotic. However the conclusion of this study was determined from only 20
patients, which is a number because there were so many restrictions for aspiration and
this research was conducted during the summer time when patients usually have no
severe symtoms.